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March 24, 2023

Brain response to food

Researchers Discover Dedicated Brain Area for Food Responses

by - Dr. Gurpreet Singh Padda, MD, MBA, MHP

Summary: A new study shows that a small area in the brain’s vision center lights up when people see food. Researchers call this cluster of food-reacting nerve cells the VFC. Knowing how people see and read food may help treat eating disorders. When we see anything, the vision center gets more active. But studies show that people, places, and words each light up different clusters of nerve cells there. The same is true for food.

Think of French fries, strawberries, and ice cream. Don’t they bring a certain feeling? A new study shows that a special group of nerve cells in the vision center lights up when you see food. Science has long known that the brain has a vision center. It handles everything we see and works with other brain parts to decide how to respond. But new studies show it is not that simple. It seems that inside the vision center, there are special areas for different kinds of things, like faces, words, bodies, and places. Food plays a huge role in health and human culture. So it seems the brain has a special part for handling food images.

Food is more than a source of nutrients for humans. It is part of culture. It even helps people bond. Food is part of who we are and how we worship, and it has many other meanings. So how did researchers find that humans have a special brain part for food? First, they gathered hundreds of public images of food and other things. Then they showed these images to the people in the study. Finally, they built a special way to track the different brain centers. The idea of a special brain area for food came from earlier studies. Those showed that one part of the brain recognizes people and places.

To see how the brain responds to food, researchers analyzed already available brain scan data (fMRI) of eight individuals who viewed thousands of images. But they knew it would be hard to find the nerve cells that respond to food, because fMRI scans are blurry. So they built a special math model that let them find specific groups of nerve cells.

They say each tiny block of a brain scan, called a voxel, holds thousands of nerve cells. The response of a few cells to what you see gets drowned out by the other cells in the same block. But new math models can pick out even small changes in a few cells within a block. Put simply, the new model can find the signals of a few nerve cells inside a crowd of them.

With this method, they found that certain groups of nerve cells in the vision center fire when people see faces, places, bodies, and words. In the same way, food images made one group of cells light up. They called it the food-specific group, or ventral food component (VFC). The researchers also tested how picky the VFC is. They wanted to see if something that only looks like food would set it off. For example, something shaped like a banana that is not a fruit. It did not. So the VFC lights up mainly for real food.

Researchers think the VFC forms in childhood, as children try different foods. So in some people, these cells may react more to pizza, and in others to fruit. How strongly these cells fire helps decide a person’s food likes. It also means that changing how these cells respond may help change food likes. It is still early, but researchers think they are on the right track. Now they must find ways to tune these cells, the VFC, that shape food choices. That may help doctors treat eating disorders and even help manage obesity.

Frequently asked questions

What part of the brain responds when you see food?

A small group of nerve cells in the vision center lights up when people look at food. Researchers named it the ventral food component (VFC). It sits next to separate clusters that respond to faces, places, bodies and words. Researchers found it by re-checking brain scans of eight people who viewed thousands of images. They used a math model sharp enough to pick out small groups of nerve cells.

Does the brain react to things that only look like food?

No. The researchers tested this directly. They showed objects that look like food but are not, such as something shaped like a banana that is not a fruit. The food cells did not light up. The VFC responds mainly to real food. That is what makes it a true food area, not a general response to food-like shapes.

Can you retrain how your brain responds to food?

Not yet. Researchers think these food cells form in childhood as children try different foods. That is why one person’s cells respond more to pizza and another’s to fruit. That response helps set food likes. So changing it could one day change what people choose to eat. The next step is finding a way to tune these cells, and that work is still in its early days.

Could this discovery help with eating disorders or obesity?

That is the goal. Knowing how people see and read food may help doctors treat eating disorders. If the VFC can be tuned, it could help shift food likes and support obesity care. For now it is early research pointing in the right direction, not a treatment you can ask for.

The Bottom Line

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Dr. Gurpreet Singh Padda, MD, MBA, MHP

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